Bloodburst should then do about 120% Max HP * 50% Overheal * (100% base + 200% crit damage) = 180% Max HP as damage that is at least 9 times the lifesteal-based damage. Build Apothecary like an attacker with 100% crit rate and 200% crit damage, and he'll heal for 120% Max HP. On the other hand, I can't think of a better pairing than Apothecary, who heals for 35% Max HP and the heal can crit. Big improvement thanks to double dipping crit damage but still not terribly impressive also consider that Defense reduction double dips and you're probably back to doing less than 5% Max HP as damage. Assuming a 200% crit damage bonus, A1 does 45% Max HP and the Bloodburst does 20% Max HP as damage. Lifesteal heals 30% of damage dealt, and the Bloodburst deals half the surplus heal as damage, so that is 15% of his A1 attack damage, or just 2.25% of his Max HP. Ironclad's A1 seems to do at most 15% Max HP as damage - my 6K HP Ironclad does about 1K damage, and I'm ignoring the ATK component. First, Ironclad's Bloodburst passive can crit.
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